originally from hartford, connecticut, comey graduated from the university of vermont as an art major with a focus on sculpture. for many years she denied her interest in fashion, instead opting to collaborate with friends on a variety of creative projects in art, costume and set design. after 10 years in vermont, comey moved to new york in 1998 to further pursue opportunities in the arts. her collaboration with the band gogol bordello, for whom she designed stage sets and costumes, garnered her a place along with the rest of the group in the 2001 whitney biennial.

in september of 2001, comey launched her eponymous collection of menswear inspired by the young music scene in new york. thanks to strong word of mouth, the collection proved a success, and she began to develop a loyal following. the natural next step for comey was to add womenswear to her burgeoning business. her collections became known for their artful custom prints, graceful modern silhouettes, a hand craftsmanship, and carefully chosen materials.

comey is a member of the cfda, and splits her time between nyc and her converted-laundromat home near a beach on long island's north fork.